Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia

Blood glutamate scavenging is a novel and attractive protecting strategy to reduce the excitotoxic effect of extracellular glutamate released during ischemic brain injury. Glutamate oxaloacetate transaminase 1 (GOT1) activation by means of oxaloacetate administration has been used to reduce the glut...

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Autors principals: Pérez-Mato, M, Ramos-Cabrer, P, Sobrino, T, Blanco, M, Ruban, A, Mirelman, D, Menendez, P, Castillo, J, Campos, F
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040715/
https://ncbi.nlm.nih.gov/pubmed/24407245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.507
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