Prognostic and Clinicopathologic Associations of BRAF Mutation in Primary Acral Lentiginous Melanoma in Korean Patients: A Preliminary Study

BACKGROUND: In the majority of melanomas, the RAS/RAF/MEK/ERK signaling pathway is constitutively activated, due to oncogenic mutations in the BRAF and NRAS genes. The BRAF mutation has been mainly described in Caucasian melanomas. However, there is a lack of study evaluating the status, and the cli...

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Bibliografiska uppgifter
Huvudupphovsmän: Hong, Jin-Woo, Lee, Suee, Kim, Dae-Cheol, Kim, Ki-Ho, Song, Ki-Hoon
Materialtyp: Artigo
Språk:Inglês
Publicerad: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2014
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037672/
https://ncbi.nlm.nih.gov/pubmed/24882974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5021/ad.2014.26.2.195
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