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ADAM10 Is the Major Sheddase Responsible for the Release of Membrane-associated Meprin A

Meprin A, composed of α and β subunits, is a membrane-bound metalloproteinase in renal proximal tubules. Meprin A plays an important role in tubular epithelial cell injury during acute kidney injury (AKI). The present study demonstrated that during ischemia-reperfusion-induced AKI, meprin A was shed...

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Bibliografiske detaljer
Main Authors: Herzog, Christian, Haun, Randy S., Ludwig, Andreas, Shah, Sudhir V., Kaushal, Gur P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036340/
https://ncbi.nlm.nih.gov/pubmed/24662289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.559088
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