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Nitric Oxide Induces Ataxia Telangiectasia Mutated (ATM) Protein-dependent γH2AX Protein Formation in Pancreatic β Cells

In this study, the effects of cytokines on the activation of the DNA double strand break repair factors histone H2AX (H2AX) and ataxia telangiectasia mutated (ATM) were examined in pancreatic β cells. We show that cytokines stimulate H2AX phosphorylation (γH2AX formation) in rat islets and insulinom...

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Detalhes bibliográficos
Main Authors: Oleson, Bryndon J., Broniowska, Katarzyna A., Schreiber, Katherine H., Tarakanova, Vera L., Corbett, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036281/
https://ncbi.nlm.nih.gov/pubmed/24610783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531228
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