Regulation of Large Conductance Ca(2+)-activated K(+) (BK) Channel β1 Subunit Expression by Muscle RING Finger Protein 1 in Diabetic Vessels

The large conductance Ca(2+)-activated K(+) (BK) channel, expressed abundantly in vascular smooth muscle cells (SMCs), is a key determinant of vascular tone. BK channel activity is tightly regulated by its accessory β1 subunit (BK-β1). However, BK channel function is impaired in diabetic vessels by...

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Bibliographic Details
Main Authors: Yi, Fu, Wang, Huan, Chai, Qiang, Wang, Xiaoli, Shen, Win-Kuang, Willis, Monte S., Lee, Hon-Chi, Lu, Tong
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Molecular Bases of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036198/
https://ncbi.nlm.nih.gov/pubmed/24570002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.520940
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