Imaging integrin alpha-v-beta-3 expression in tumors with an (18)F-labeled dimeric RGD peptide

Integrin α(v)β(3) receptors are expressed on activated endothelial cells during neovascularization to maintain tumor growth. Many radiolabeled probes utilize the tight and specific association between the arginine-glycine-aspartatic acid (RGD) peptide and integrin α(v)β(3), but one main obstacle for...

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Main Authors: Dijkgraaf, Ingrid, Terry, Samantha, McBride, William J., Goldenberg, David M., Laverman, Peter, Franssen, Gerben M., Oyen, Wim J. G., Boerman, Otto C.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034708/
https://ncbi.nlm.nih.gov/pubmed/23606427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmmi.1523
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