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Design and physicochemical characterisation of novel dissolving polymeric microneedle arrays for transdermal delivery of high dose, low molecular weight drugs

We describe formulation and evaluation of novel dissolving polymeric microneedle (MN) arrays for the facilitated delivery of low molecular weight, high dose drugs. Ibuprofen sodium was used as the model here and was successfully formulated at approximately 50% w/w in the dry state using the copolyme...

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Bibliografische gegevens
Hoofdauteurs: McCrudden, Maelíosa T.C., Alkilani, Ahlam Zaid, McCrudden, Cian M., McAlister, Emma, McCarthy, Helen O., Woolfson, A. David, Donnelly, Ryan F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier Science Publishers 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034161/
https://ncbi.nlm.nih.gov/pubmed/24556420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.02.007
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