Disease Exacerbation of Multiple Sclerosis is Characterized by Loss of Terminally Differentiated Autoregulatory CD8+ T cells

Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system (CNS). Although its etiology remains unknown, pathogenic T cells are thought to underlie MS immune pathology. We recently showed that MS patients harbor CNS-specific CD8+ Tregs that are deficient during d...

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Detalhes bibliográficos
Main Authors: Cunnusamy, Khrishen, Baughman, Ethan J., Franco, Jorge, Ortega, Sterling B., Sinha, Sushmita, Chaudhary, Parul, Greenberg, Benjamin M., Frohman, Elliot M., Karandikar, Nitin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024444/
https://ncbi.nlm.nih.gov/pubmed/24657764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2014.03.005
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