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A graph theoretic approach to utilizing protein structure to identify non-random somatic mutations
BACKGROUND: It is well known that the development of cancer is caused by the accumulation of somatic mutations within the genome. For oncogenes specifically, current research suggests that there is a small set of "driver" mutations that are primarily responsible for tumorigenesis. Further,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4024121/ https://ncbi.nlm.nih.gov/pubmed/24669769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-86 |
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