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Enzyme-Directed Assembly of Nanoparticles in Tumors Monitored by In Vivo Whole Animal and Ex Vivo Super Resolution Fluorescence Imaging

Matrix metalloproteinase enzymes, overexpressed in HT-1080 human fibrocarcinoma tumors, were used to guide the accumulation and retention of an enzyme-responsive nanoparticle in a xenograft mouse model. The nanoparticles were prepared as micelles from amphiphilic block copolymers bearing a simple hy...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Chien, Miao-Ping, Carlini, Andrea S., Hu, Dehong, Barback, Christopher V., Rush, Anthony M., Hall, David J., Orr, Galya, Gianneschi, Nathan C.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021865/
https://ncbi.nlm.nih.gov/pubmed/24308273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja408182p
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