Targeting gallbladder cancer: oncolytic virotherapy with myxoma virus is enhanced by rapamycin in vitro and further improved by hyaluronan in vivo

BACKGROUND: Gallbladder carcinoma (GBC) is highly lethal, and effective treatment will require synergistic anti-tumor management. The study is aimed at investigating the oncolytic value of myxoma virus (MYXV) infection against GBC and optimizing MYXV oncolytic efficiency. METHODS: We examined the pe...

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Bibliographische Detailangaben
Hauptverfasser: Weng, Mingzhe, Gong, Wei, Ma, Mingzhe, Chu, Bingfeng, Qin, Yiyu, Zhang, Mingdi, Lun, Xueqing, McFadden, Grant, Forsyth, Peter, Yang, Yong, Quan, Zhiwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021541/
https://ncbi.nlm.nih.gov/pubmed/24725816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-82
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