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Collapse of a Long Axis: Single-Molecule Förster Resonance Energy Transfer and Serpin Equilibrium Unfolding

[Image: see text] The energy required for mechanical inhibition of target proteases is stored in the native structure of inhibitory serpins and accessed by serpin structural remodeling. The overall serpin fold is ellipsoidal with one long and two short axes. Most of the structural remodeling require...

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Detalles Bibliográficos
Main Authors: Liu, Lu, Werner, Michael, Gershenson, Anne
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020580/
https://ncbi.nlm.nih.gov/pubmed/24749911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401622n
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