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Human Herpesvirus 6A Infection in CD46 Transgenic Mice: Viral Persistence in the Brain and Increased Production of Proinflammatory Chemokines via Toll-Like Receptor 9

Human herpesvirus 6 (HHV-6) is widely spread in the human population and has been associated with several neuroinflammatory diseases, including multiple sclerosis. To develop a small-animal model of HHV-6 infection, we analyzed the susceptibility of several lines of transgenic mice expressing human...

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Autors principals: Reynaud, Joséphine M., Jégou, Jean-François, Welsch, Jérémy C., Horvat, Branka
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019085/
https://ncbi.nlm.nih.gov/pubmed/24574405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03763-13
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