Axons degenerate in the absence of mitochondria in C. elegans

Many neurodegenerative disorders are associated with mitochondrial defects [1–3]. Mitochondria can play an active role in degeneration by releasing reactive oxygen species and apoptotic factors [4–7]. Alternatively, mitochondria can protect axons from stress and insults, for example by buffering cal...

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Hlavní autoři: Rawson, Randi L., Yam, Lung, Weimer, Robby M., Bend, Eric G., Hartwieg, Erika, Horvitz, H. Robert, Clark, Scott G., Jorgensen, Erik M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018749/
https://ncbi.nlm.nih.gov/pubmed/24631238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.02.025
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