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Protection Against Epithelial Damage During Candida albicans Infection Is Mediated by PI3K/Akt and Mammalian Target of Rapamycin Signaling

Background. The ability of epithelial cells (ECs) to discriminate between commensal and pathogenic microbes is essential for healthy living. Key to these interactions are mucosal epithelial responses to pathogen-induced damage. Methods. Using reconstituted oral epithelium, we assessed epithelial gen...

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Bibliographic Details
Main Authors: Moyes, David L., Shen, Chengguo, Murciano, Celia, Runglall, Manohursingh, Richardson, Jonathan P., Arno, Matthew, Aldecoa-Otalora, Estibaliz, Naglik, Julian R.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017362/
https://ncbi.nlm.nih.gov/pubmed/24357630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit824
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