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L1 retrotransposition: The snap-velcro model and its consequences
LINE-1 (L1) elements are the only active and autonomous transposable elements in humans. The core retrotransposition machinery is a ribonucleoprotein particle (RNP) containing the L1 mRNA, with endonuclease and reverse transcriptase activities. It initiates reverse transcription directly at genomic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4014453/ https://ncbi.nlm.nih.gov/pubmed/24818067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mge.28907 |
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