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Ganoderma lucidum polysaccharides reduce methotrexate-induced small intestinal damage in mice via induction of epithelial cell proliferation and migration

AIM: To study the effects of Ganoderma lucidum polysaccharides (Gl-PS) on methotrexate (MTX)-induced small intestinal damage in mice and the underlying mechanisms. METHODS: BALB/c mice were used for in vivo study. The mice were administered with Gl-PS (50, 100, or 200 mg/kg, ig) for 10 d, and inject...

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Bibliographic Details
Main Authors: Chen, Li-hua, Lin, Zhi-bin, Li, Wei-dong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010208/
https://ncbi.nlm.nih.gov/pubmed/22019957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.126
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