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The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond

Nucleotide-binding oligomerization domain (NOD)-containing protein-like receptors (NLRs) are a recently discovered class of innate immune receptors that play a crucial role in initiating the inflammatory response following pathogen recognition. Some NLRs form the framework for cytosolic platforms ca...

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Detalhes bibliográficos
Main Authors: Conforti-Andreoni, Cristina, Ricciardi-Castagnoli, Paola, Mortellaro, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003142/
https://ncbi.nlm.nih.gov/pubmed/21258359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2010.81
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