Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8(+) T lymphocytes in human non-small cell lung cancer

T-cell tolerance is an important mechanism for tumor escape, but the molecular pathways involved in T-cell tolerance remain poorly understood. It remains unknown whether the inhibitory immunoreceptor programmed death-1 (PD-1) plays a role in conditions of human non-small cell lung cancer (NSCLC). In...

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Hlavní autoři: Zhang, Yan, Huang, Shengdong, Gong, Dejun, Qin, Yanghua, Shen, Qian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002677/
https://ncbi.nlm.nih.gov/pubmed/20514052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2010.28
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