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Independent Adipogenic and Contractile Properties of Fibroblasts in Graves’ Orbitopathy: An In Vitro Model for the Evaluation of Treatments

Graves’ orbitopathy (GO) is a disfiguring and sometimes blinding disease, characterised by inflammation and swelling of orbital tissues, with fibrosis and adipogenesis being predominant features. Little is known about the disease aetiology and the molecular mechanisms driving the phenotypic changes...

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Main Authors: Li, He, Fitchett, Caroline, Kozdon, Katarzyna, Jayaram, Hari, Rose, Geoffrey E., Bailly, Maryse, Ezra, Daniel G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994071/
https://ncbi.nlm.nih.gov/pubmed/24751986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095586
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