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Morphine Induces Redox-Based Changes in Global DNA Methylation and Retrotransposon Transcription by Inhibition of Excitatory Amino Acid Transporter Type 3–Mediated Cysteine Uptake
Canonically, opioids influence cells by binding to a G protein–coupled opioid receptor, initiating intracellular signaling cascades, such as protein kinase, phosphatidylinositol 3-kinase, and extracellular receptor kinase pathways. This results in several downstream effects, including decreased leve...
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Hlavní autoři: | , , , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3990020/ https://ncbi.nlm.nih.gov/pubmed/24569088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.091728 |
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