Selected ABCB1, ABCB4 and ABCC2 Polymorphisms Do Not Enhance the Risk of Drug-Induced Hepatotoxicity in a Spanish Cohort

BACKGROUND AND AIMS: Flawed ABC transporter functions may contribute to increased risk of drug-induced liver injury (DILI). We aimed to analyse the influence of genetic variations in ABC transporters on the risk of DILI development and clinical presentations in a large Spanish DILI cohort. METHODS:...

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Bibliographic Details
Main Authors: Ulzurrun, Eugenia, Stephens, Camilla, Ruiz-Cabello, Francisco, Robles-Diaz, Mercedes, Saenz-López, Pablo, Hallal, Hacibe, Soriano, German, Roman, Eva, Fernandez, M. Carmen, Lucena, M. Isabel, Andrade, Raúl J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986086/
https://ncbi.nlm.nih.gov/pubmed/24732756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094675
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