Structure–Activity Relationships among Antifungal Nylon-3 Polymers: Identification of Materials Active against Drug-Resistant Strains of Candida albicans

[Image: see text] Fungal infections are a major challenge to human health that is heightened by pathogen resistance to current therapeutic agents. Previously, we were inspired by host-defense peptides to develop nylon-3 polymers (poly-β-peptides) that are toxic toward the fungal pathogen Candida alb...

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Hauptverfasser: Liu, Runhui, Chen, Xinyu, Falk, Shaun P., Mowery, Brendan P., Karlsson, Amy J., Weisblum, Bernard, Palecek, Sean P., Masters, Kristyn S., Gellman, Samuel H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985965/
https://ncbi.nlm.nih.gov/pubmed/24606327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500036r
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