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Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline
Piwi proteins and Piwi-interacting RNAs (piRNAs) repress transposition, regulate translation, and guide epigenetic programming in the germline. Here, we show that an evolutionarily conserved Tudor and KH domain-containing protein, Tdrkh (a.k.a. Tdrd2), is required for spermatogenesis and involved in...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
European Molecular Biology Organization
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3981179/ https://ncbi.nlm.nih.gov/pubmed/23714778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.121 |
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