Abrogating G(2)/M checkpoint through WEE1 inhibition in combination with chemotherapy as a promising therapeutic approach for mesothelioma

Malignant mesothelioma (MM) is a very aggressive asbestos-related neoplasm of the serous membranes, whose incidence is increasing worldwide. Although the introduction of new drug combinations, such as cisplatin plus pemetrexed/gemcitabine, has determined an improvement in the patient quality of life...

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Bibliographische Detailangaben
Hauptverfasser: Indovina, Paola, Marcelli, Eleonora, Di Marzo, Domenico, Casini, Nadia, Forte, Iris Maria, Giorgi, Francesca, Alfano, Luigi, Pentimalli, Francesca, Giordano, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979815/
https://ncbi.nlm.nih.gov/pubmed/24365782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27623
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