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Single cell expression quantitative trait loci and complex traits

The recently developed ability to quantify mRNA abundance and noise in single cells has allowed the effect of heritable variations on gene function to be re-evaluated. A recent study has shown that major sources of variation are masked when gene expression is averaged over many cells. Heritable vari...

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Bibliographic Details
Main Author: Petretto, Enrico
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978606/
https://ncbi.nlm.nih.gov/pubmed/23998908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm476
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