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Probabilistic approaches to alignment with tandem repeats

BACKGROUND: Short tandem repeats are ubiquitous in genomic sequences and due to their complex evolutionary history pose a challenge for sequence alignment tools. RESULTS: To better account for the presence of tandem repeats in pairwise sequence alignments, we propose a simple tractable pair hidden M...

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Autori principali: Nánási, Michal, Vinař, Tomáš, Brejová, Broňa
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975930/
https://ncbi.nlm.nih.gov/pubmed/24580741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-9-3
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