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The Pro-Apoptotic Role of the Regulatory Feedback Loop between miR-124 and PKM1/HNF4α in Colorectal Cancer Cells

Accumulating evidence indicates that miRNA regulatory circuits play important roles in tumorigenesis. We previously reported that miR-124 is correlated with prognosis of colorectal cancer due to PKM-dependent regulation of glycolysis. However, the mechanism by which miR-124 regulates apoptosis in co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sun, Yan, Zhao, Xiaoping, Luo, Man, Zhou, Yuhong, Ren, Weiying, Wu, Kefen, Li, Xi, Shen, Jiping, Hu, Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International (MDPI) 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975400/
https://ncbi.nlm.nih.gov/pubmed/24619225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15034318
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