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Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation
In mouse mid-gestational embryos, definitive hematopoietic stem progenitor cells are derived directly from a very small proportion of the arterial endothelium. However, the physiological mechanisms restraining excessive endothelial-hematopoietic transition remain elusive. We show here that genetic d...
Gorde:
| Egile Nagusiak: | , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society of Hematology
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3975256/ https://ncbi.nlm.nih.gov/pubmed/24553180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-526053 |
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