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Growth Differentiation Factor (GDF)-15 Blocks Norepinephrine-induced Myocardial Hypertrophy via a Novel Pathway Involving Inhibition of Epidermal Growth Factor Receptor Transactivation

Accumulating evidence suggests that growth differentiation factor 15 (GDF-15) is associated with the severity and prognosis of various cardiovascular diseases. However, the effect of GDF-15 on the regulation of cardiac remodeling is still poorly understood. In this present study, we demonstrate that...

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Detalhes bibliográficos
Main Authors: Xu, Xin-ye, Nie, Ying, Wang, Fang-fang, Bai, Yan, Lv, Zhi-zhen, Zhang, You-yi, Li, Zi-jian, Gao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974979/
https://ncbi.nlm.nih.gov/pubmed/24554716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.516278
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