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JAK1/3 signaling pathways are key initiators of T(H)2 differentiation and lung allergic responses
BACKGROUND: Janus kinases (JAK) are regulators of signaling through cytokine receptors. The importance of JAK1/3 signaling on Th2 differentiation and development of lung allergic responses has not been investigated. OBJECTIVE: To examine a selective JAK1/3 inhibitor (R256) on differentiation of Th s...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972277/ https://ncbi.nlm.nih.gov/pubmed/24365136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.10.036 |
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