A Simple Scalable Association Hypothesis Test Combining Gene-wide Evidence From Multiple Polymorphisms

AIMS: In single-nucleotide polymorphism (SNP) scans, SNP-phenotype association hypotheses are tested, however there is biological interpretation only for genes that span multiple SNPs. We demonstrate and validate a method of combining gene-wide evidence using data for high-density lipoprotein choles...

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Hauptverfasser: Vaidya, Dhananjay, Yanek, Lisa R., Mathias, Rasika A., Moy, Taryn F., Becker, Diane M., Becker, Lewis C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969754/
https://ncbi.nlm.nih.gov/pubmed/24688980
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