Загрузка...

Synthesis and in vivo evaluation of N-ethylamino-2-oxo-1,2-dihydro-quinoline-3-carboxamide for inhibition of intestinal tumorigenesis in APC(Min/+) mice

A selective KGFR tyrosine kinase inhibitor, N-ethylamino-2-oxo-1,2-dihydro-quinoline-3-carboxamide, was synthesized and its possible inhibitory effects on the development of colon polyps and colorectal tumors was examined in APC(Min/+) mice, a mouse model of human intestinal familial adenomatous pol...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Pathuri, Gopal, Li, Qian, Mohammed, Altaf, Gali, Hariprasad, Pento, J. Thomas, Rao, Chinthalapally V.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966088/
https://ncbi.nlm.nih.gov/pubmed/24507628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.01.042
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!