Modeling Hippocampal Neurogenesis Using Human Pluripotent Stem Cells

The availability of human pluripotent stem cells (hPSCs) offers the opportunity to generate lineage-specific cells to investigate mechanisms of human diseases specific to brain regions. Here, we report a differentiation paradigm for hPSCs that enriches for hippocampal dentate gyrus (DG) granule neur...

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Bibliographic Details
Main Authors: Yu, Diana Xuan, Di Giorgio, Francesco Paolo, Yao, Jun, Marchetto, Maria Carolina, Brennand, Kristen, Wright, Rebecca, Mei, Arianna, Mchenry, Lauren, Lisuk, David, Grasmick, Jaeson Michael, Silberman, Pedro, Silberman, Giovanna, Jappelli, Roberto, Gage, Fred H.
Format: Artigo
Language:Inglês
Published: Elsevier 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964286/
https://ncbi.nlm.nih.gov/pubmed/24672753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.01.009
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