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Streptococcal-vimentin cross-reactive antibodies induce microvascular cardiac endothelial proinflammatory phenotype in rheumatic heart disease
Rheumatic heart disease (RHD) is characterized by the presence of anti-streptococcal group A antibodies and anti-endothelial cell antibodies (AECA). Molecular mimicry between streptococcal antigens and self proteins is a hallmark of the pathogenesis of rheumatic fever. We aimed to identify, in RHD p...
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| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2013
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949629/ https://ncbi.nlm.nih.gov/pubmed/23663103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12135 |
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