Streptococcal-vimentin cross-reactive antibodies induce microvascular cardiac endothelial proinflammatory phenotype in rheumatic heart disease

Rheumatic heart disease (RHD) is characterized by the presence of anti-streptococcal group A antibodies and anti-endothelial cell antibodies (AECA). Molecular mimicry between streptococcal antigens and self proteins is a hallmark of the pathogenesis of rheumatic fever. We aimed to identify, in RHD p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Delunardo, F, Scalzi, V, Capozzi, A, Camerini, S, Misasi, R, Pierdominici, M, Pendolino, M, Crescenzi, M, Sorice, M, Valesini, G, Ortona, E, Alessandri, C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2013
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949629/
https://ncbi.nlm.nih.gov/pubmed/23663103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12135
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