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Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies
Irisin was identified as a myokine secreted by contracting skeletal muscle, possibly mediating some exercise health benefits via ‘browning’ of white adipose tissue. However, a controversy exists concerning irisin origin, regulation and function in humans. Thus, we have explored Fndc5 gene and irisin...
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Main Authors: | , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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John Wiley & Sons Ltd
2014
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948565/ https://ncbi.nlm.nih.gov/pubmed/24297848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.264655 |
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