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Permeability Transition Pore-Mediated Mitochondrial Superoxide Flashes Mediate an Early Inhibitory Effect of Aβ1–42 on Neural Progenitor Cell Proliferation

Cellular damage by reactive oxygen species (ROS) and altered neurogenesis are implicated in the etiology of AD and the pathogenic actions of amyloid β-peptide (Aβ); the underlying mechanisms and the early oxidative intracellular events triggered by Aβ are not established. In the present study, we fo...

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Detalhes bibliográficos
Main Authors: Hou, Yan, Ghosh, Paritosh, Wan, Ruiqian, Ouyang, Xin, Cheng, Heping, Mattson, Mark P., Cheng, Aiwu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946227/
https://ncbi.nlm.nih.gov/pubmed/24325797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.11.002
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