Adeno-associated Virus–mediated Delivery of a Recombinant Single-chain Antibody Against Misfolded Superoxide Dismutase for Treatment of Amyotrophic Lateral Sclerosis

There is emerging evidence that the misfolding of superoxide dismutase 1 (SOD1) may represent a common pathogenic event in both familial and sporadic amyotrophic lateral sclerosis (ALS). To reduce the burden of misfolded SOD1 species in the nervous system, we have tested a novel therapeutic approach...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Patel, Priyanka, Kriz, Jasna, Gravel, Mathieu, Soucy, Geneviève, Bareil, Christine, Gravel, Claude, Julien, Jean-Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944333/
https://ncbi.nlm.nih.gov/pubmed/24394188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.239
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky