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Calcium dependent regulation of Rab activation and vesicle fusion by an intracellular P2X ion channel

Rab GTPases play key roles in the delivery, docking and fusion of intracellular vesicles. However, the mechanism by which spatial and temporal regulation of Rab GTPase activity is controlled is poorly understood. Here we describe a mechanism by which localized calcium release through a vesicular ion...

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Autors principals: Parkinson, Katie, Baines, Abigail E., Keller, Thomas, Gruenheit, Nicole, Bragg, Laricia, North, R. Alan, Thompson, Christopher R.L.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942655/
https://ncbi.nlm.nih.gov/pubmed/24335649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2887
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