Aspirin and clonidine in non-cardiac surgery: acute kidney injury substudy protocol of the Perioperative Ischaemic Evaluation (POISE) 2 randomised controlled trial

INTRODUCTION: Perioperative Ischaemic Evaluation-2 (POISE-2) is an international 2×2 factorial randomised controlled trial of low-dose aspirin versus placebo and low-dose clonidine versus placebo in patients who undergo non-cardiac surgery. Perioperative aspirin (and possibly clonidine) may reduce t...

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Autori principali: Garg, Amit X, Kurz, Andrea, Sessler, Daniel I, Cuerden, Meaghan, Robinson, Andrea, Mrkobrada, Marko, Parikh, Chirag, Mizera, Richard, Jones, Philip M, Tiboni, Maria, Rodriguez, Raul Gonzalez, Popova, Ekaterina, Rojas Gomez, Maria Fernanda, Meyhoff, Christian S, Vanhelder, Tomas, Chan, Matthew T V, Torres, David, Parlow, Joel, de Nadal Clanchet, Miriam, Amir, Mohammed, Bidgoli, Seyed Javad, Pasin, Laura, Martinsen, Kristian, Malaga, German, Myles, Paul, Acedillo, Rey, Roshanov, Pavel, Walsh, Michael, Dresser, George, Kumar, Priya, Fleischmann, Edith, Villar, Juan Carlos, Painter, Tom, Biccard, Bruce, Bergese, Sergio, Srinathan, Sadeesh, Cata, Juan P, Chan, Vincent, Mehra, Bhupendra, Leslie, Kate, Whitlock, Richard, Devereaux, P J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2014
Soggetti:
Renal Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939660/
https://ncbi.nlm.nih.gov/pubmed/24568963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-004886
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