Cyclooxygenase-2 inhibitor is a robust enhancer of anticancer agents against hepatocellular carcinoma multicellular spheroids

PURPOSE: Celecoxib, an inhibitor of cyclooxygenase-2 (COX2), was investigated for enhancement of chemotherapeutic efficacy in cancer clinical trials. This study aimed to determine whether celecoxib combined with 5-fluorouracil or sorafenib or gefitinib is beneficial in HepG2 multicellular spheroids...

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Autori principali: Cui, Jie, Guo, Ya-Huan, Zhang, Hong-Yi, Jiang, Li-Li, Ma, Jie-Qun, Wang, Wen-Juan, Wang, Min-Cong, Yang, Cheng-Cheng, Nan, Ke-Jun, Song, Li-Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938498/
https://ncbi.nlm.nih.gov/pubmed/24591842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S56115
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