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Determination of parameter identifiability in nonlinear biophysical models: A Bayesian approach

A major goal of biophysics is to understand the physical mechanisms of biological molecules and systems. Mechanistic models are evaluated based on their ability to explain carefully controlled experiments. By fitting models to data, biophysical parameters that cannot be measured directly can be esti...

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Detalhes bibliográficos
Main Authors: Hines, Keegan E., Middendorf, Thomas R., Aldrich, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933937/
https://ncbi.nlm.nih.gov/pubmed/24516188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311116
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