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Determination of parameter identifiability in nonlinear biophysical models: A Bayesian approach

A major goal of biophysics is to understand the physical mechanisms of biological molecules and systems. Mechanistic models are evaluated based on their ability to explain carefully controlled experiments. By fitting models to data, biophysical parameters that cannot be measured directly can be esti...

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Bibliografiska uppgifter
Huvudupphovsmän: Hines, Keegan E., Middendorf, Thomas R., Aldrich, Richard W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933937/
https://ncbi.nlm.nih.gov/pubmed/24516188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311116
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