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Simplification of Reversible Markov Chains by Removal of States With Low Equilibrium Occupancy
We present a practical method for simplifying Markov chains on a potentially large state space when detailed balance holds. A simple and transparent technique is introduced to remove states with low equilibrium occupancy. The resulting system has fewer parameters. The resulting effective rates betwe...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3930476/ https://ncbi.nlm.nih.gov/pubmed/22820127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2012.07.007 |
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