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Simplification of Reversible Markov Chains by Removal of States With Low Equilibrium Occupancy

We present a practical method for simplifying Markov chains on a potentially large state space when detailed balance holds. A simple and transparent technique is introduced to remove states with low equilibrium occupancy. The resulting system has fewer parameters. The resulting effective rates betwe...

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Main Authors: Ullah, Ghanim, Bruno, William J, Pearson, John E
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930476/
https://ncbi.nlm.nih.gov/pubmed/22820127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2012.07.007
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