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A dual-targeting triplebody mediates preferential redirected lysis of antigen double-positive over single-positive leukemic cells
The single-chain triplebody HLA-ds16-hu19 consists of three single-chain Fv (scFv) antibody fragments connected in a single polypeptide chain. This protein with dual-targeting capacity mediated preferential lysis of antigen double-positive (dp) over single-positive (sp) leukemic cells by recruitment...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929450/ https://ncbi.nlm.nih.gov/pubmed/24135631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.26768 |
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