Fabrication of nanoadjuvant with poly-ε-caprolactone (PCL) for developing a single-shot vaccine providing prolonged immunity

PURPOSE: The aim of the study was to load a model antigen, tetanus toxoid (TT), in poly-ε-caprolactone nanoparticles (PCL NPs) of two size ranges, ie, mean 61.2 nm (small) and 467.6 nm (large), and study its effect on macrophage polarization as well as antigen presentation in human monocyte-derived...

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Главные авторы: Prashant, Chandravilas Keshvan, Bhat, Madhusudan, Srivastava, Sandeep Kumar, Saxena, Ankit, Kumar, Manoj, Singh, Amar, Samim, Mohammed, Ahmad, Farhan Jalees, Dinda, Amit Kumar
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2014
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928464/
https://ncbi.nlm.nih.gov/pubmed/24611010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S55892
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