In vitro evaluation of clot quality and stability in a model of severe thrombocytopenia: effect of fibrinogen, factor XIII and thrombin-activatable fibrinolysis inhibitor

BACKGROUND: The treatment options in severe thrombocytopenia (platelet count ≤20×10(9)/L) are limited. The aim of this study was to investigate ways of improving blood clotting and stability in reconstituted thrombocytopenia. MATERIALS AND METHODS: Thrombocytopenia (platelets [16±4]×10(9)/L) was cre...

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Main Authors: Shenkman, Boris, Einav, Yulia, Livnat, Tami, Budnik, Ivan, Martinowitz, Uriel
Format: Artigo
Jezik:Inglês
Izdano: Edizioni SIMTI - SIMTI Servizi Srl 2014
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926734/
https://ncbi.nlm.nih.gov/pubmed/24333083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2450/2013.0068-13
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