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Targeting the Insulin-like Growth Factor Receptor: Developing Biomarkers from Gene Expression Profiling

Overwhelming evidence implicates insulin-like growth factor (IGF) signaling in the growth and survival of many types of human cancer cells. Numerous inhibitors of the IGF1 receptor (IGF1R) have been developed, and they displayed remarkable antineoplastic activity in preclinical models and promising...

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Autors principals: Boone, David N., Lee, Adrian V.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926653/
https://ncbi.nlm.nih.gov/pubmed/22471706
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